A matched case-control study on perinatal risk factors of early onset thrombocytopenia in full-term small for gestational age infants / 临床儿科杂志

Objective To explore the perinatal risk factors of early onset thrombocytopenia (EOT) in full-term small for gestational age infants. Methods A 1:1 or 1:2 matched case control study was carried out. A total of 93 full-term small for gestational age infants with EOT were selected from April 2008 to July 2014 as the case group, and the non EOT full-term small for gestational age infants with the birth weight difference <250 g and the gestational age difference <3 days were selected as the control group. The clinical data during perinatal period and laboratory examination results after admission were collected retrospectively. And the differences between the two groups were compared. Results The incidence of intrauterine distress (41.9％ vs. 25.8％, χ2=7.35, P=0.007), amniotic fluid contamination (39.8％ vs. 27％, χ2=4.66, P=0.031), and early-onset sepsis (39.8％ vs. 27％, χ2=4.66, P=0.031) were significantly higher in the case group than those in the control group. Conditional logistics regression analysis showed that intrauterine distress (β=0.60, OR=1.82, 95％CI=1.04～3.17, P=0.035) and early-onset sepsis (β=1.69, OR=5.44, 95％CI=1.11～26.76, P=0.037) were related to EOT. Conclusions Intrauterine distress and early-onset sepsis are risk factors for the onset of EOT in full-term small for gestational age infants.

Application of diary therapy for out-of-hospital rehabiditation of schizophrenia patients with first hospitalization / 中国实用护理杂志

Objective We discussed the influence of diary therapy for out-of-hospital rehabilitation of schizophrenia patients with first hospitalization. Methods Ninety schizophrenia patients with first hospitaliza-tion and who were during rehabilitation period were randomized into the intervention group and the control group with 45 cases in each group.The two groups both received systemic antipsychotics medication.The control group adopted general health education while the intervention group got diary therapy based upon general health education.The treatment effect was evaluated by medical and nursing staff with abundant experience using the self-medication compliance questionnaire,the brief psychiatric rating scale(BPRS)and social disability screening schedule(SDSS)at the first day,6th month and first year after intervention. Results The total score of BPRS,SDSS,medication compliance and relapse rate in the intervention group was statistically better than those of the control group. Conclusions Diary therapy could facilitate the recovery of racial function,improve the medica-tion compliance,reduce the relapse rate and increase life quality for schizophrenia patients.